Large rocks and a sandy beach with sparse vegetation.

Find hotels in Isla Santa María from CA $67

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 26 - Aug 27
Tomorrow
Aug 27 - Aug 28
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Filter by

Star rating

Guest rating

Our top choices for Isla Santa María hotels

1. Twin Hotel Galapagos

Twin Hotel Galapagos
Bella Vista
United States
Janet
CA $84
CA $84 total
Aug 30 - Aug 31
Twin Hotel Galapagos

2. Capitan Max B&B

Capitan Max B&B
Puerto Ayora
Canada
Christie
CA $104
CA $104 total
Aug 28 - Aug 29
Capitan Max B&B

3. White House Galapagos

White House Galapagos
Puerto Ayora
Canada
Christianne
CA $50
CA $70 total
Sep 2 - Sep 3
White House Galapagos

4. Posada del Mar

Posada del Mar
Puerto Ayora
United States
Grace
CA $101
CA $101 total
Aug 31 - Sep 1
Posada del Mar

5. Suymar Ecolodge Galapagos

Suymar Ecolodge Galapagos
Bella Vista
Canada
Carole
CA $88
CA $122 total
Aug 28 - Aug 29
Suymar Ecolodge Galapagos

6. Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
Puerto Ayora
United States
Kurush
CA $375
CA $417 total
Aug 28 - Aug 29
Angermeyer Waterfront Inn

7. Hotel Fiesta

Hotel Fiesta
Puerto Ayora
United States
Daniel
CA $180
CA $180 total
Sep 27 - Sep 28
Hotel Fiesta

8. Galapagos Verde Azul

Galapagos Verde Azul
Puerto Ayora
Canada
sierra
CA $116
CA $116 total
Aug 28 - Aug 29
Galapagos Verde Azul

9. Hotel Palace Galapagos

Hotel Palace Galapagos
Puerto Ayora
United States
Tomoko
CA $96
CA $96 total
Aug 30 - Aug 31
Hotel Palace Galapagos

10. Hotel Cucuve

Hotel Cucuve
Puerto Ayora
United States
Tatiana
CA $250
CA $277 total
Aug 28 - Aug 29
Hotel Cucuve

11. Hotel Ninfa

Hotel Ninfa
Puerto Ayora
United States
Jonathan
CA $182
CA $182 total
Aug 28 - Aug 29
Hotel Ninfa

12. Maidith Galapagos Inn

Maidith Galapagos Inn
Puerto Ayora
United Kingdom
Thomas
CA $174
CA $174 total
Sep 7 - Sep 8
Maidith Galapagos Inn

13. HOTEL CROSSMAN

HOTEL CROSSMAN
Puerto Ayora
Canada
PENGFEI
CA $93
CA $93 total
Sep 27 - Sep 28
HOTEL CROSSMAN

14. Hostal Sir Francis Drake

Hostal Sir Francis Drake
Puerto Ayora
United States
Dr Farkas
CA $76
CA $76 total
Aug 28 - Aug 29
Hostal Sir Francis Drake

15. Plaza Luna Suites

Plaza Luna Suites
Puerto Ayora
United Kingdom
Daniel
CA $262
CA $262 total
Sep 26 - Sep 27
Plaza Luna Suites

16. Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
Puerto Ayora
United Kingdom
Roberto
CA $156
CA $156 total
Aug 28 - Aug 29
Fernandina Hotel & Spa Galápagos

17. Hostal North Seymour

Hostal North Seymour
Puerto Ayora
United States
Maria del Pilar
CA $76
CA $76 total
Aug 31 - Sep 1
Hostal North Seymour

18. Hotel Coloma Galapagos

Hotel Coloma Galapagos
Puerto Ayora
United States
Elsa Margarita
CA $126
CA $126 total
Sep 27 - Sep 28
Hotel Coloma Galapagos

19. Ikala Galapagos Hotel

Ikala Galapagos Hotel
Puerto Ayora
United States
Maria
CA $371
CA $408 total
Sep 27 - Sep 28
Ikala Galapagos Hotel

20. Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
Puerto Ayora
United States
Conrad
CA $762
CA $840 total
Sep 5 - Sep 6
Finch Bay Galapagos Hotel
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties
Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.
Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

See all hotels in Isla Santa María
A beach with sea lions resting on the sand and a cruise ship in the distance.
Photo by Delen Wong

Top Isla Santa María Hotel Reviews

Posada del Mar

Posada del Mar

10/10 Excellent
"great location and very bright room. Staff are very helpful and reliable. I had great time here. Only issue is the shower water is hard to adjust."
bin 4-night trip
Posted 1 day ago
Posada del Mar
Hotel Ninfa

Hotel Ninfa

10/10 Excellent
"Staff was really friendly and helpful"
Kleber 4-night trip
Posted 3 days ago
Hotel Ninfa
Hotel Fiesta

Hotel Fiesta

10/10 Excellent
"Clean, safe, very friendly staff. close to port and main shopping/dining. lovely pool, affordable drinks at bar and good breakfast."
Daniel 2-night trip
Posted 4 days ago
Hotel Fiesta
Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos

8/10 Good
"Everything was convenient and easy. Staff were very helpful. All went well"
Prithvish 3-night trip
Posted 6 days ago
Fernandina Hotel & Spa Galápagos
Hotel Coloma Galapagos

Hotel Coloma Galapagos

8/10 Good
"quirky simple hotel. Owner helped us carry the luggage up the stairs. it's on Baltra Ave near more locally owned businesses but close to the Malecon (walkway along the shore) and all the tourist places. Very friendly staff (Sandra & Magali) who cooked a nice breakfast for us every morning. Good reasonably priced seafood meal down the street at the Rustica. We stopped in the Bike shop also down the street about renting E-bikes and received some more restaurant suggestions. People said Buenas Dias to us in the street."
jack 3-night trip
Posted 7 days ago
Hotel Coloma Galapagos
Galapagos Verde Azul

Galapagos Verde Azul

8/10 Good
"Our room was spotless. The floors were mopped everyday. All of the wildlife in the area was magical."
Stan 6-night trip
Posted 8 days ago
Galapagos Verde Azul
Hotel el descanso del Guia

Hotel el descanso del Guia

10/10 Excellent
"Really quirky hotel which we loved. Very central and staff were great."
Gordon 3-night trip
Posted 12 days ago
Hotel el descanso del Guia
Maidith Galapagos Inn

Maidith Galapagos Inn

10/10 Excellent
"Pros: quiet location but still a close walk to town, excellent rotating breakfast options, warm pool for the kids to play in, very clean and comfortable, lots of character! Cons: none, we loved it all!"
Gail 3-night trip
Posted 2 weeks ago
Maidith Galapagos Inn
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

10/10 Excellent
"Overall a perfect 3 night stay after a 5 day busy (and amazing) Galapagos cruise! One of our rooms was kindly upgraded at check-in. We were greeted with delicious cool drinks and hot face towels, and very kind staff. Daily house keeping (with water replenishment) and very comfortable rooms with gorgeous views. The king bed was very comfortable in our suite, perhaps not as comfortable in our teens’ room but they did fine. Very quiet and peaceful, slept soundly. Always felt safe. Excellent breakfast choices and lovely staff. Also had lunch and dinner at Eloise. Watched sharks swim by at night, and during the day a seal slept on the restaurant patio between meal service. Water taxi to town was easy. Took a $5 taxi to Charles Darwin Center and walked back into town, stopping at 1835 restaurant for a delicious lunch. Spent time at the beach near Finch Bay and had one lunch at their swimming pool patio bar. Went to The Rock (Asian Fusion) for one dinner on the main drive. We ventured into some more local blocks one night but it was quite noisy with everyone playing loud music in their restaurants and pushing menus at you as you walked past. It was ok but we preferred the main road restaurant experiences."
Christina 3-night trip
Posted 2 weeks ago
Angermeyer Waterfront Inn

More cheap stays in Isla Santa María

Hotel Brisas Del Pacifico

Hotel Brisas Del Pacifico

General Rodriguez Puerto Ayora
CA $67
CA $67 total
Aug 28 - Aug 29
7.6/10 Good! (82 reviews)
Hotel Brisas Del Pacifico
White House Galapagos

White House Galapagos

Calle Roberto Schiess e Isla Duncan Puerto Ayora Santa Cruz
CA $50
CA $70 total
Sep 2 - Sep 3
9/10 Wonderful! (106 reviews)
White House Galapagos
Hostal Sir Francis Drake

Hostal Sir Francis Drake

Av. Baltra y Charles Binford Puerto Ayora Galapagos
CA $76
CA $76 total
Aug 28 - Aug 29
Hostal Sir Francis Drake
Lonesome George Ecolodge

Lonesome George Ecolodge

Avenida Cucuve S/N and Floreana Puerto Ayora Santa Cruz
CA $138
CA $138 total
Aug 28 - Aug 29
Lonesome George Ecolodge
Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel

C/ Floreana Y Matazarnos Puerto Ayora Islas Galápagos
CA $266
CA $266 total
Sep 7 - Sep 8
10/10 Exceptional! (42 reviews)
Acacia Galapagos Boutique Hotel
El Barranco Galapagos

El Barranco Galapagos

Los colonos Puerto Ayora Galapagos
CA $281
CA $281 total
Aug 31 - Sep 1
9.8/10 Exceptional! (87 reviews)
El Barranco Galapagos

Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Finch Bay Galapagos Hotel and Maidith Galapagos Inn. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 215 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.